Welp, I had to play Harvest Moon 64 on a K6-2 450 mhz in earlier 2001, until I got my Athlon 900 mhz, which was in June, 2001.
I was lucky to get 15 FPS with the K6-2 450 mhz. And because the audio is supposed to sync with the video, a slow down of less than about 20 FPS would definitely cause audio stuttering.
I had to use a bigger audio buffer with Nemu 0.7a, at the time, back in 2001. But would still be at least minor audio stuttering. Me remembering that makes me look like an old fart, lol.
With Nintendo 64 emulation, the processor often mattered more than the video card, even though it requires hardware 3D accelerated video, with at least a GeForce, TNT2 or equivalent for it to work reasonably.
The Rare games are known for making me get a processor upgrade.
Even though Conker's Bad Fur Day and Banjo Kazooie were OK with a 900 mhz processor.