@Retrolux according to a reddit post about using SGSSAA , you aren't meant to use the "Antialiasing-Transparency Multisampling: Enabled" flag in Nvidia Profile Inspector when using a "Antialiasing-Transparency Supersampling:" value that isn't "Off".
Problem #1 - The two are meant to be used exclusively, not with both at the same time.
The nvidia control panel also shows this, because you have to choose between multisampling and supersampling in the same drop down list, so you can't select both.
Problem #2 - Your README recommends using 2xQ & Off, 4xQ & 2x SSGA, 8xQ & 4x SSGA
However, only the 8xQ setting is purely MSAA and 4xQ doesn't even exist in the profile inspector.
I assume you meant for all settings to be MSAA, in which case you need to correct the recommended settings in the README.
Problem #3 - That reddit post also says "The Antialiasing - Setting and Antialiasing - Transparency Supersampling can be set to any value,
but they must match! 2x MSAA must have 2x SGSSAA and so on!"
Since your README recommends using un-equal pairs of MSAA and SGAA.
I'm not entirely sure why they are better when used with an equal number of samples, but since everything in that reddit post/guide has been correct so far, while your instructions have been wrong, it's safe to assume that they are right again.
So unless I'm missing something you should probably correct your README, since it might get people some free FPS and avoid any weird issues with the AA.