I don't own a Fanatec wheel so I'm not really sure if I understand "adjust the wheel Sensitivity." correctly.
The 900° rotation is indeed the same as I use with my G25 in all games, so I'd stick with that and adjust steering lock accordingly in-game.
In the GTL in-game settings there's two other settings: One is "Steering sensitivity", and the other is "Speed Sensitive Steering" Not sure which one you mean so I'll try to explain both. I'm not at my gaming rig ATM so I must do this from memory. This may get a bit technical and I'm no native speaker, but just try to bear with me.
Steering Sensitivity controls how linear the steering of the car will be. If the steering is perfectly linear, when you turn the wheel 10% of its maximum rotation, the cars front wheels will turn exactly 10% of their max. angle; when you turn the wheel 50% of its maximum rotation, the cars front wheels will turn exactly 50% of their max. angle. So if you turn the wheel 225° in one direction, the cars front wheels will turn exactly 5° in that direction if you have 20° steering lock (you have 900° rotation, 450° to left and 450° to right, so 50% equals 225° in one direction, Steering Lock 20° is lock-to-lock, so max. 10° left and 10° right. 50% of that is 5° turn of the front wheels)
In GTL, IIRC a Steering Sensitivity setting of 50% makes it perfectly linear. With that setting, 900° rotation with 20° steering lock will feel exactly the same as 450° rotation with 10° steering lock.
When you use a higher setting than 50%, the steering becomes non-linear and more sensitive around the center. So you only have to turn your wheel, say, 150° to get the cars wheels to turn that same 5°. So when you start turning your wheel from the center all the way to the left, the first half rotation from 0° to 180° will have more effect on the cars front wheels than the last half rotation from 270° to 450°
When you use a Steering Sensitivity setting below 50% the opposite will happen, small wheel movements around the center position will have less effect than small wheel movements all the way to the left or right.
You guessed it, I have Steering Sensitivity at 50%. Always.
Speed Sensitive Steering is a bit different, it controls how much your cars front wheels will turn depending on your speed. When you're driving 10 mph and you suddenly turn your wheel 90° to the left, the car will start making a nice clean sharp turn. If you do the same when driving 120 mph, you will most likely crash and wreck your car. Speed Sensitive Steering is there to prevent that. When enabled, it will not allow your cars front wheels to turn very far, depending on your speed. The higher your speed, the further you will have to turn your steering wheel to make it through a certain corner. Or, the higher your speed, the less your cars front wheels will turn when you turn your steering wheel 90° to the left or right.
As this is not a feature I've seen on a real car I have this swithched off, which I think is setting it at 0%.
Hope I still make sense to you.
And to anyone reading this, please correct me if I'm wrong.