Thought I would make a thread for this in the hope that someone having the same problem and tearing their hair out finds the way I solved this useful/works for them. The problem - My G25 stopped centering it suddenly was 10 - 15 degrees out -and whatever I did - unplug, reboots changing Logitech Profiles - nothing would work. Solution (for me at least) - using windows 'Programs and Features' I UNINSTALLED the Logitech Gaming Software (v 5.10 in my case). No reboot needed - I then went to 'Game Controllers' where my G25 is listed (highlight G25 if you have multiple controllers) Click Properties - Then the Settings tab - then Calibrate - This then takes you through windows own calibration for the wheel - which allows you to set the wheel at the centre. Apply. I then tested the wheel in the same game that had caused me problems to make sure it really was centered (Although I'm now sure I could have missed this step out). I then closed the game again and re-installed the Logitech Gaming Software (all my profiles were still there after reinstalling) - and it all worked properly. Hope this post stops someone going nuts and tearing their hair out like I almost did over this issue !